[[(4-Methylphenyl)sulfonyl]oxy]carbamic acid cyclohexylmethyl ester
Cyclohexylmethyl N-tosyloxycarbamate
CAS: 869111-41-1
Molecular Formula: C15H21NO5S
[[(4-Methylphenyl)sulfonyl]oxy]carbamic acid cyclohexylmethyl ester - Names and Identifiers
[[(4-Methylphenyl)sulfonyl]oxy]carbamic acid cyclohexylmethyl ester - Physico-chemical Properties
| Molecular Formula | C15H21NO5S |
| Molar Mass | 327.4 |
| Melting Point | 89-91℃ |
[[(4-Methylphenyl)sulfonyl]oxy]carbamic acid cyclohexylmethyl ester - Introduction
Cyclohexylmethyl N-tosyloxycarbamate, also known as Cyclohexylmethyl N-tosyloxycarbamate, is an organic compound. Its chemical formula is C13H19NO5S and its molecular weight is 297.36g/mol.
The following are the properties of Cyclohexylmethyl N-tosyloxycarbamate:
-Appearance: Usually white crystalline solid
-Melting point: about 85-87 ℃
-Solubility: Can be dissolved in common organic solvents, such as ether, methylene chloride and methanol
-Stability: relatively stable under dry and dark conditions, but sensitive to humid and acidic environments
Cyclohexylmethyl N-tosyloxycarbamate can be used in a number of reactions and transformations in organic synthesis, including:
-As a protecting group: The tosyl acyl protection on the hydroxylamine group has certain stability and can be used to protect other reactive groups, such as amine or alcohol groups, in some synthetic steps.
-Nucleophilic functional group transfer reagent: This compound can introduce the hydroxylamine group on it to other positions in the molecule through a nucleophilic functional group transfer reaction to achieve specific stereo or conformational changes.
-Intermediates: Cyclohexylmethyl N-tosyloxycarbamate can be further transformed into other organic compounds for the synthesis of drugs, natural products or novel organic molecules.
The method of preparing Cyclohexylmethyl N-tosyloxycarbamate is generally carried out by the following steps:
1. p-Toluenesulfonyl chloride (tosyl chloride) was added to hydroxylamine (Hydroxylamine).
2. The reaction product is heated to generate N-p-toluenesulfonylhydroxylamine.
3. reacting N-p-toluenesulfonylhydroxylamine with N-tert-butoxycarboyl chloride (tert-butyl chloroformate) to generate Cyclohexylmethyl N-tosyloxycarbamate.
When using or handling Cyclohexylmethyl N-tosyloxycarbamate, please note the following safety information:
-Avoid direct contact with skin and eyes to prevent irritation and damage.
-Wear appropriate protective gloves, glasses and laboratory clothing during operation.
-Operate under well-ventilated conditions to avoid inhalation of toxic gases.
-Storage should be closed in a dry, cool, dark place.
-During storage and handling, please observe the relevant safety operation regulations and operating procedures.
The following are the properties of Cyclohexylmethyl N-tosyloxycarbamate:
-Appearance: Usually white crystalline solid
-Melting point: about 85-87 ℃
-Solubility: Can be dissolved in common organic solvents, such as ether, methylene chloride and methanol
-Stability: relatively stable under dry and dark conditions, but sensitive to humid and acidic environments
Cyclohexylmethyl N-tosyloxycarbamate can be used in a number of reactions and transformations in organic synthesis, including:
-As a protecting group: The tosyl acyl protection on the hydroxylamine group has certain stability and can be used to protect other reactive groups, such as amine or alcohol groups, in some synthetic steps.
-Nucleophilic functional group transfer reagent: This compound can introduce the hydroxylamine group on it to other positions in the molecule through a nucleophilic functional group transfer reaction to achieve specific stereo or conformational changes.
-Intermediates: Cyclohexylmethyl N-tosyloxycarbamate can be further transformed into other organic compounds for the synthesis of drugs, natural products or novel organic molecules.
The method of preparing Cyclohexylmethyl N-tosyloxycarbamate is generally carried out by the following steps:
1. p-Toluenesulfonyl chloride (tosyl chloride) was added to hydroxylamine (Hydroxylamine).
2. The reaction product is heated to generate N-p-toluenesulfonylhydroxylamine.
3. reacting N-p-toluenesulfonylhydroxylamine with N-tert-butoxycarboyl chloride (tert-butyl chloroformate) to generate Cyclohexylmethyl N-tosyloxycarbamate.
When using or handling Cyclohexylmethyl N-tosyloxycarbamate, please note the following safety information:
-Avoid direct contact with skin and eyes to prevent irritation and damage.
-Wear appropriate protective gloves, glasses and laboratory clothing during operation.
-Operate under well-ventilated conditions to avoid inhalation of toxic gases.
-Storage should be closed in a dry, cool, dark place.
-During storage and handling, please observe the relevant safety operation regulations and operating procedures.
Last Update：2024-04-09 15:18:00
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